The practice of self-medicating with cannabidiol (CBD) is now becoming popular among people. As this compound is found to be able to naturally relieve different illnesses like vomiting, nausea, inflammation, pain, sleep disorders, stress, PTSD, depression, anxiety, etc., people began to use CBD for such diseases instead of other prescription medications.
But some people are concerned about the effects CBD creates in their body. A lot of people worry that CBD can lead to the development of tolerance like other medications when used for a long time. So we analyze CBD tolerance and how to overcome this problem to use this compound effectively. This can be useful for you to know how to derive the benefits of CBD without worrying about tolerance.
People found to develop tolerance to cannabinoids like THC, which is the major psychoactive compound in the cannabis plant. This particular cannabinoid has the ability to directly bind with the CB1 receptors in the human body that are designed to receive the natural cannabinoids produced by the body. But THC is a phytocannabinoid that has the same structural features as the endocannabinoids produced by the human body. Hence, it can regulate the functioning of the endocannabinoid system by affecting these receptors.
It is found that THC can cause the downregulation of the endocannabinoid system and prevents it from becoming overactive. This can reduce the ability of the endocannabinoid system to produce cannabinoids. As a result of this, people who regularly use THC might develop tolerance to this compound and they will have to increase the dosage for getting the same results as before. This can also have a negative impact on the ability of the endocannabinoid system to learn and adapt to different factors like stress, as this system has become greatly dependent on THC.
You have to be cautious when using products that contain THC, as they can lead to unwanted effects.
The story of CBD is entirely different from that of THC. This compound does not directly bind with the cannabinoid receptors. Instead, it can boost the ability of these receptors to utilize the cannabinoids produced by the body more efficiently. So the chance for your body to develop tolerance to this compound is low when compared to THC.
But some people are found to develop tolerance to CBD when they use it for a long time. However, this tolerance is usually temporary and can go away if you stop the use of CBD for a short period of time. Therefore, you won’t have to worry about increasing the amount of this compound even if you use it for a long time.